Background & Aim:Teachers knowledge and attitudes about AIDS is one of the most important factors influencing communities attitudes and awareness about this disease. Educating teachers about AIDS helps expanding AIDS education plans by promoting knowledge and enhancing attitude of teachers.

Material & Methods: in this Quasi experimental study all of the Khatham city high school teachers enrolled (120 subjects include 70 female, and 50 male). Data gathering instruments were demographic, AIDS knowledge and attitude self designed questionnaires. Questionnaires completed by subjects in two times (before education and two weeks after education). Education was included two 45 min sessions based on AIDS hand book education that developed by researchers. The data were analyzed by SPSS 13 software, using paierd T-test.

Results: mean age of subjects was 34.87±7.98. 58.3% were female, 85.8% of them were graduated and 85.8% were married. Result shows that there is significant relationship between knowledge scores of subjects in pre and post education using paired T-test (p<0.05). Also there was significant relationship between attitude scores in pre and post education (p<0.05).

Conclusion: this study showed that education can improve knowledge and attitude of teachers about AIDS.