Background & Aim: Diabetes mellitus is a common metabolic disorder that has negative effects on psychological condition, interpersonal, family and social relationship and in general, on psychological well-being. Quality of life and blood sugar metabolism control are two important indexes in diabetes treatment. The purpose of this study was to investigate the relationship between quality of life and mental health in diabetes patients.

Material & Methods: This cross- sectional study was conducted on 90 diabetes patients in 2015-16 who referred to clinics of Yasouj. Participants were selected with convenience sampling method. Data gathering was accomplished by two instruments: short form quality of life questionnaire (Sf-36) and general health questionnaires (GHQ). Finally data were analyzed by Spearman correlation coefficient and T-test using SPSS-17software.

Results: The result showed that most domains in quality of life were correlated with mental health domains. General health perception and physical function domains were correlated significantly with 3 domains of mental health: anxiety, social function and depression. Mental health domain of quality life were significantly correlated with Somatoform symptoms (p<0.02). Finally, social function was significantly correlated with social dysfunction domain of mental health (p<0.05). Also, anxiety and somatoform domains of mental health had been significantly correlated in women than men (p=0.006), (p=0.025). Physical function domain is more significant in men than women (p=0.03) and bodily pain is more significant in women than men (p=0.001).

Conclusion: According to the results, Diabetes is a chronic disease that affects patients' quality of life and mental health. Thus, attention to different dimensions of psychological health is necessary and interventions based on quality of life can be more effective.