Background & Aim: Different studies support the role of nutritional factors as one of the important probable factor in Multiple Sclerosis (MS) etiology. The objective of this study was to determine of MS patient's nutritional status referred to MS Association in Tehran City in 2008.

Material & Methods: This research was a descriptive and analytical study. In this study 2oo men and women who were suffering from M.S disease were selected. Study instrument was questionnaire and method was interviews. Data were obtained through easy, the data were analyzed with SPSS version 11.5 through descriptive and Inferential statistical methods.

Results: The results showed that nutritional status in the sample (%78) was relatively desirable. Findings showed there were significant relation between marriage status (P=0/015), family income and nutrition (P=0/001)

Conclusion: Suitable Food and feeding habits can effect on prevention and signs and symptoms due to MS. Therefore, improvement in Food and feeding habits in these patients seem to be essential that we can access to it with holistic educational programs.